No matter which charity you choose, your unused clothes will do more good in a donation bin than sitting in your closet. Try to schedule a clear-out once a year for everyone in your household. Donating annually helps ensure that the clothes you donate are still in style.
For tax purposes, retain your receipt, and keep track of how many clothes you donate and their condition. This info will come in handy when you file and protect you in case you are audited by the IRS.
Have you donated your clothes to a charity before?