I've had de quervain problems on the right hand. My right hand movement is limited and I can't do any rough work. It will cause great pain. This pain occurs spontaneously when I wake up from sleep. Hope my friends can help me so that I can make treatment and this right hand is important for me to do everything. I suffer from pain every night and shed tears. 😭😭😭. What is De Quervain’s tenosynovitis is a painful condition that affects the tendons in wrist. It occurs when the 2 tendons around the base of thumb become swollen. The swelling causes the sheaths (casings) covering the tendons to become inflamed. This puts pressure on nearby nerves, causing pain and numbness. Your goodness is all that God can repay. Thank You For Support..