Mrs. Sultana Dairmaan Khan Sultan Jan, 41 years old lady is a diagnosed as case of Precursor B-Cell Acute Lymphoblastic Leukemia (Philadelphia positive) as per diagnosed in Sheikh Khalifa Medical City, Abu Dhabi with complex karyotype. She received 03 cycles of Hyper-CVAD regimen along with TKI therapy (Dasatinib). She has achieved only 1.8 log reduction in disease burden assessed molecularly. MRD status by Flow cyrtometery / PCR is not available. She has a 6/6 HLA-Matched sibling donor available.

If she achieves complete remission after completion of induction therapy, she will require allogenic transplant toconsolidate the disease. She has a very high risk disease, the success rate of transplant in this case is approximately 30 %. There is a high risk of graft failure & acute GvHD, which can be life threatening.

The approximate package cost of this treatment is Rs: 4,400,000/- (Rupees Four Million Four Hundred Thousand only) payable in advance. The cost includes drugs, BMT procedure charges, blood products transfusion charges, lab investigations, 4 weeks hospital stay, doctor's consultation and pre-transplant workup of Rs: 200,000/-.

Post BMT follow up treatment will be charged at actual. The cost of TK Inhibitor (Dasatinib) is not included in this letter, which patient may need in post transplant.

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Contact: Dairmaan: +971 50 659 9275

Salman Raja +92 300 8224664

Anila Hussian : +41791945909